Odorant/Pheromone Binding Proteins

OBPs, members of lipocalin protein family, are highly diverse, small, water-soluble, globular, ligand specific proteins present in the mucus fluid produced by nasal glands in vertebrates and in the sensillar lymph in insects. OBPs act a “carrier” to transport odorants across the hydrophilic mucus layer and release them in vicinity of their respective ORs. OBPs are highly selective, as they have unique ligand binding profile. OBPs functionality and expression are not limited to olfaction mechanism and olfactory organs. They are found to be involved in various other functions like measuring odorant concentration, deactivating odorants, etc. and found in taste organs, venom glands, sex hormone glands, etc of insects. Structurally OBPs are made up of eight antiparallel β-sheets folded into a continuous hydrogen-bonded β-barrel and a α-helical domain at the carboxyl terminal. OlfactionBase comprises of 2418 Odorant binding proteins, 399 Pheromone Binding proteins and 14 receptors from 189 species.

obp
Sr. No UniProt Organism Type Length Sequence
151 A0A194PHT0 Papilio xuthus Odorant binding 121 MTKQQLKNSGKLIKKTCMPKNDVTEDQVGEIDKGKFIEDRNVMCYIACVYSMGQAVKNNKIVFDAMIKQVDMMFPPEMKEPYKAAIEKCKGVAKNYKDICEASYWTAKCIYEADTENFFFP
152 A0A194PIR2 Papilio xuthus Odorant binding 121 MTRQQLKNSAKMLKKTCMAKNDVTEDLIGDIEKGKFIEQRNVMCYIACIYQMTQIVKNNKLSYEASLKQVDLMYPPELKASVKVSIENCKDISKKYADICEASYWTAKCLYDDNPKDFIFA
153 A0A194QLX3 Papilio machaon Odorant binding 121 MTRQQLKNSGKIMKKSCMPKNDVTEEQVGEIENGKFIEDRNVMCYIACVYSMSQVVKNNKLNYEALIKQVDVMFPAEMRDAVKAAAANCKDVGKKYKDICEASYWTAKCMYDFDPKNFVFP
154 A0A1B0D4L5 Phlebotomus papatasi Odorant binding 121 ITVEEAKELAKIFSEPCRVKYRISNELIEEVNKGNFPDDRSLKCYANCMLEMTQTVSRGRINYRMSLTQIDLLLPEEMKESAKKTLDACRGSMKGIKDYCEASYNYVQCMYKVNRKYFYFP
155 A0A1B0FD15 Glossina morsitans morsitans Odorant binding 121 MSERCMRLEKVPDRYKAQFTEFQFPNDPIVHKYILCVNRELQIWDNNQGFDIEKIYQQYKGRANEEVVLPIISQCNQDAKQRNYELWCYKAFLCILDTQVGEWFKEDVRRQQTRTLTNGHQ
156 A0A212EMX0 Danaus plexippus plexippus Odorant binding 121 MTRAQLKKTMTIMKNQCMPKHNVNNDKVGQIEQGVFIEDHDVMCYIACIYKTIQVVKNNRLDKDLISKQIDALYPPELKESTKEAVSKCIKEQAKYEDPCAGIFYACKCLYEDNPANFIFP
157 A0A212EMZ7 Danaus plexippus plexippus Odorant binding 121 MTRQQIKNSSKMLKKNCMGKNDVTEDMVGEIDKGKFIEDKNVMCYIACIYQMSQLVKNNKLNYEASIKQVDLMFPPDMKEAMKASIENCKDISKKYKDICEASYWTAKCIYDDNPKNFIFA
158 A0A2A4K7Q1 Heliothis virescens Odorant binding 121 MTRDQIKNSGKLIKKTCMTKNDLSEDQVKDVDKGKFIEEKPFMCYIACVYKMGQTIKGNTVNYDMMLKQVELMFPNEMKAPMKAAIEHCRPVAKKYKDVCEVSYWTAKCIYDFDPANFMFP
159 A0A2A4K934 Heliothis virescens Odorant binding 121 MTMKQIRNTGKMMRKSCQPKNNVSDEQIDPIAEGVFNEDKEVKCYMACIMKMANTIKNGKLNYEAAIKQADLLLPDDIKEPAKEAITACRKVADAYKDICDASFHITKCIYTQNPAIFYFP
160 B0WU10 Culex quinquefasciatus Odorant binding 121 MKFPVALGLFVAVVTADMELTPDERNCQMRQRASDKDVEMFHTMQRPVERTTKCYYDCMMQVMGYSNGKRFIRDRFEDFYLSAAKNDDQRRTIRHLADKCDGTEHDDACELAADIVACIRR
161 B0XC63 Culex quinquefasciatus Odorant binding 121 MKCDSWATLLLTVLIWYAKFCGHDCVDILEEAKKGVFPNEKNFKCYVSCLLDMMQATKRGKISYEKSLKQIDTLLPDDFKPDFRNGLEACKDVAQGVKDHCESAYVLLNCFYQNNPKFIFP
162 B8ZWK1 Bombyx mori Odorant binding 121 MSRQQLKNSGKMLKKQCMGKNDVTEEEIGDIEKGKFIEQKNVMCYIACIYQMTQIIKNNKISYEASIKQIDLMYPPELKESAKASAGRCKDVSKKYKDICEASYWTAKCMYEDNPKDFIFA
163 E9J9T6 Solenopsis invicta Odorant binding 121 KSLILVCVSVVLTQLVVVSFSAKTDEIDWTTVHDDLRKLGATFRKKCLAETGVTIDKLEGAEMGQFPDDRKLACYFKCVMEKGGVMKKDGTINYKVLAKLLPQAYKQIGIDMMDECRDIGK
164 H9JFQ4 Bombyx mori Odorant binding 121 MTRQQLKNSGKIMKKTCMPKNDVTEEEIGQIEQGKFLEQRNVMCYIACIYTVTQVVKNNKLSYDAVIKQVDVMFPAEMRPAVKAAAENCKDISKTFKDICEASYWTAKCMYDFDPKNFVFP
165 H9JFQ5 Bombyx mori Odorant binding 121 MTKQQIKNSGKILKKACISKNDVTEDQISDIDKGKFIEDKNVMCYIACVYSMSQVVKNNKFVHDAMVKQVDMMFPTEMRDAVKASIANCRGVAKNYKDICEASFWTAKCMYEFDPANFVFA
166 M4Y1X0 Cnaphalocrocis medinalis Odorant binding 121 MTRQQLKNSSKMLKKNCMAKHSVTEDQIGSIEKGKFVEERPVMCYIACIYQMTQVVKNNKLNYEASIKQVDMMYPNELKESVKKSIDKCKTVSDKYKDLCEASYWTAKCIYEDNPKDFIFA
167 A7UR17 Anopheles gambiae Odorant binding 121 SITQEQLEKTARTFRQVCQPKHKISDEVADAVNRGVFADTKDFKCYVSCLLDIMQVARKGKVNYEKSLKQIDTMLPDHMKPAFRAGLEACKSAAQGVKDHCEAAAILLQCFYKNNPKFVFP
168 T1GN15 Megaselia scalaris Odorant binding 121 MNTFNTLLALVGFVAFVQSASITKEMQEKFMVVAKECQGQTGASDGDLANLIKHNPTGTKEGKCMLSCIMTKVDTQDSNGKLKKEGSMHIAMAMTKNDPAEMKIAEEIIDACVGIAVSDDA
169 A0A067QSS4 Zootermopsis nevadensis Odorant binding 122 MVSAIVSYAFEAIQDCAQENKVSLMKISTSLIFSRTGADKNSKCAIACVMERFYLIMGDQVETAMLAEVINMIPIEALKVPVTQLVNTCGKKGPDKCENASTFIFCLKQNGMTTATKALFRG
170 A0A0K8W793 Bactrocera latifrons Pheromone binding 122 MAEAAIEDCYEDSAQGVKVQITDESFDEILKGSRTNLSHNAKCLRYCIMRKNGLLSVDNSIDEENILQIFEIIHPQIKKDSLLDVLHKCSRETDKQTDNCERAFVATSCILRELQADGVTDI
171 A0A182F3H0 Anopheles albimanus Odorant binding 122 MQSLRFVSVAVLLLGISSSLAFFTEEQHEIAKNLADACQKELGVELPADFCAIQCIFAKVGFTDAETGVANRAVLAQKLSKGNPVEKAEQFADLCANNEGTSKCDKAFSLHQCYHKNKSIFN
172 A0A182GWY2 Aedes albopictus Odorant binding 122 MTGHSIYTKSQVREIFSAGKECMRILNIPLESDIVERVLYNRDVVKDEETLKYFDCGTKKLGWVDSEGNLEISPMVEFFSRNIPRKQVQDVLEKCKTSFDGANVGEKMFNYQQCFFEKKKFK
173 A0A182GWY3 Aedes albopictus Odorant binding 122 MLFFQTTYTKSQIREIFSAGKECMRTLNIPLQSDIIERVLFNRSVVKDEETLKYMECASKKMGWIDNEGKLVIPPMIEYFSRNALQKYVEEVLEQCKIFYEDANAGEKMFNYHQCYFENKKF
174 A0A182H0D8 Aedes albopictus Odorant binding 122 MNPNQLGQNLLAAYNVCRTEYNVDMDTYNAIRNGDFSIRTPFIECFGDCLVKKAGFMNDDLSFNKDVIVKFVSRFIKPEDSESVYNQCTADVAPVLCATAFDVYQCIYENALSKWGTKRNGK
175 A0A194QMH1 Papilio machaon Odorant binding 122 MTRQQLKNSAKMLKKTCMAKNDVTEDLIGDIQKGKFIEERNVMCYIACIYQMSQIVKNNKLSYEASLKQVDMMYPPELKTSVKASIENCKDISKKYADICEASYWTAKCLYEDNPKDFIFA
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