Odorant/Pheromone Binding Proteins

OBPs, members of lipocalin protein family, are highly diverse, small, water-soluble, globular, ligand specific proteins present in the mucus fluid produced by nasal glands in vertebrates and in the sensillar lymph in insects. OBPs act a “carrier” to transport odorants across the hydrophilic mucus layer and release them in vicinity of their respective ORs. OBPs are highly selective, as they have unique ligand binding profile. OBPs functionality and expression are not limited to olfaction mechanism and olfactory organs. They are found to be involved in various other functions like measuring odorant concentration, deactivating odorants, etc. and found in taste organs, venom glands, sex hormone glands, etc of insects. Structurally OBPs are made up of eight antiparallel β-sheets folded into a continuous hydrogen-bonded β-barrel and a α-helical domain at the carboxyl terminal. OlfactionBase comprises of 2418 Odorant binding proteins, 399 Pheromone Binding proteins and 14 receptors from 189 species.

obp
Sr. No UniProt Organism Type Length Sequence
51 A0A182HZM4 Anopheles arabiensis Odorant binding 113 MFDPYVTIALSSRCCARDLYVPEDLIELYKERIFPDDQLTCCVFRCFGMRLGIYDDVKGFDVDKQYERVKDWLSVDEDTYKRGVKNCIRNVLRGRTLNNCEKAYLILNQCQVT
52 A0A182PLI9 Anopheles epiroticus Odorant binding 113 MAKTSAMMRTVCMGKHKVGEDLINDLGRGVFADVKELKCYANCVLEMMQAIKKGKVIADSAIKQVDLLIPTEIATPTIKAFDECRDSGIKNPCDGAYALLKCLHANNPKYFFA
53 A0A182TWP5 Anopheles melas Odorant binding 113 MLHEICIAESGASEEQLRTCLDGTVPTDPAAKCYIHCLFDKIDVVDEQTGRILLDRLLYIIPDDVKAAVDHLTRECSHIVTPDKCETAYETVKCYFNAHDEVIKFCHLLVLE
54 A0A1I8NKL7 Musca domestica Odorant binding 113 MERIKLIQVYVGIWDLNMKCLLHCVYAKNNAIDKNGWPTLDGLVDFYSGGVNEHGFFMATLRSVNLCLRAVTNKYHVNRRQLPEKGESCDLAFDVFDCISDQITGYCLDQYKA
55 A7VJH9 Anomala schonfeldti Pheromone binding 113 MLKLVLLLSLGIYVPAVMCMSEEMEELAKQLHNDCVAQTGVDEAHITTVKDQKGFPDDEKFKCYLKCLMTEMAIVGDDGIVDVEAAVGVLPDEYKAKAEPVMRKCGVKPGANP
56 H9JIE1 Bombyx mori Odorant binding 113 MYAHDKLSDMIADQCLNEMYPRSKRLEIEESDEPCIIFCVLKKFGIMSPTGVINLEAYRKRVQLPEQLAQRNSINDFGSACLESAEATQHKQDVCKKAKVFNECTHLYKILLK
57 Q8MP03 Anomala octiescostata Pheromone binding 113 MLKLVVLLTLGIYVPTVMCMSEEMEELAKQLHNDCVAQTGVDEAHITTVKDQKGFPDDEKFKCYLKCLMTEMAIVGDDGVVDVEAAVGVLPDEYKAKAEPVMRKCGVKPGANP
58 Q8MP04 Anomala cuprea Pheromone binding 113 MLKLVVLLTLGIYVPTVMCMSEEMEELARQLHNDCVAQTGVDEAHITTVKDQKGFPDDEKFKCYLKCLMTEMAIVGDDGVVDIEAAVGVMPDEYKAKAEPVIRKCGVKPGANP
59 A0A084VA42 Anopheles sinensis Odorant binding 114 MDDIARGMRKVCLSKSKISEEIADYPSKGIFPDDQEFKCYVACLMDLSQTSKKGKLNYEAAVRQISILPEEYKQPFRQGLEACRNAANDVSDRCEVAYTLLKCFFKASPKFFFP
60 A0A182LXS7 Anopheles culicifacies Odorant binding 114 MNRSAKSSDGTLDQMAKTSAMMRSVCMGKHKADEALIDGLGRGEFPDTKEIKCYANCVLEMMQAMKKGKIMADSAIKQIDLLIPTEIAEPTIKAFDGCRDSGKCWSSKGWINMN
61 A0A182X7D8 Anopheles quadriannulatus Odorant binding 114 MNFFTVSAIALVAIIGSIQAEHSPLPHYFVRKSFPEAQAECAVYLQVPDDRLQRYMREGYPDEPEVHCLVLCVLENLRAWENATDVFSQCFGNTDLYKHFLAVFKDAAMTYTRQ
62 A0A1B0FPX4 Glossina morsitans morsitans Odorant binding 114 MMRNGCAPKFKLTTEQIDGLRVGNFDENNKDLKACFIIVYITQLAGTLTKKGELSAQKALAQIPMILPVEMQKVALASLEHCKDIQKNYKDPCDRLFFTTKCVYEYAPDDFTFP
63 A7VJH6 Anomala rufocuprea Pheromone binding 114 EEMEELAKQLHNDCVAQTGVDEAHITTVKDQKGFPDDEKFKCYLKCLMTEMAIVGDDGIVDVEAAVGVLPDEYKAKAEPVMRKCGVKPGANPCDNVYQTHKCYYDTDPQSYMIV
64 A7VJI1 Anomala schonfeldti Pheromone binding 114 MKSLVVVIVLVGLYSPVILGETLKEHGEKVMEKVIDYATSCADSLKVSPEDIKLLMEKKLPASKEGQCIPSCVHKKFGILKADGTIDREHRDSDMEEIKAIDEEVYNKMNSVWE
65 B0WJP7 Culex quinquefasciatus Odorant binding 114 MRGALIRGLTVCHNETYVSEETIVRFRDDEDFDGTPELGCYLYCIFREKNFWINSRNELHLTKALEIVPVDFEQQALKMGLKCLKVKGDDNCARALWYHNCWKKSSPAHYFLI
66 F4WR96 Acromyrmex echinatior Pheromone binding 114 ADIKRECRKQTNVSWASLKQLKAGNIEQHDIKLKCYLKCFLAKNGILNENNSIDVEKVLRHLPRNLQESSRKILHRCKSIQSENACDKAFQIATCYIKGQPDVCITIIQIYYYY
67 A0A151IRX0 Trachymyrmex cornetzi Pheromone binding 115 MLEMVQADKERCMAEHGTSQASIDEVNDGKLSNDRSITCYMNCLLDAFSLVDEEGNLEADMLISVIPEQFQEIGNKILNKCAKQDGADACEKIYEIAKCVQGTVPEVNRFIVSSQ
68 A0A158NUC8 Atta cephalotes Odorant binding 115 MLEHERIFKRECRKQTNVSWASLKQLQAGNTEQHDMKLKCYLKCFMVKSGIINENSNLDVEKVLRYLPYSIQESSRKILHQCKSIQSENTCDKAFQIAICYFKEQPDVLKSVSFI
69 A0A182FQ66 Anopheles albimanus Odorant binding 115 MAKTSAMMRSVCIGKHKANVDLVAGLGNGQFVDVKELKCYANCVLEMMQAMKKGKVNADSAIKQIELLMPTDIAEPTITAFDLCRDSANGIKNHCDAAYALLQCLHKSNPKYFFA
70 A0A194PVY0 Papilio xuthus Odorant binding 115 MPAKFLEKSKLVGEKCVKEAGAESDFLEHLFPWNYPKTEAYEKSLLCFATTIGLANQDGIFYTEKVHPVFSSSENFEEIKKAFAECNAMRGNSPQDTAFIISECFFDKAPIRLTM
71 A0A194QEV4 Papilio xuthus Pheromone binding 115 MGLPDTIYNDFYNFWSEDYVITNNATGCAFICIAARLNLIVNGPNSHINLNTFFQYSRKRGADDQTAKRLLQLLRYCEGQSRDETDTCMRVVHCANCFRREIHALNWAPKVEEIP
72 A0A1B0CD50 Lutzomyia longipalpis Odorant binding 115 MKKAGMLVRSICQPKFNIPDDQADGYAKGIFPDDKNSKCYVNCVFENMQSMKRGKFQFEATKKQVELLLEGELRDANIKAFEACKSCTDGIKDHCEAGFSLLLCLHKNTKLFVFP
73 A0A1B0FMT9 Glossina morsitans morsitans Odorant binding 115 MPLLDLKETESFWELCQQSHNITDEEFENFNAFQSIDMEPDRKFKCYAHCLLSNLKYLNTFSGKFDIEDFKQQDGIEDEDVAVIAKCKKLYDNINDPCEYGFNILQCILMFEPTE
74 A0A1I8NKN6 Musca domestica Odorant binding 115 MARYIVEISADEISQSAACLQENNLTKNELLEILDSIRAGAKEVDSRVKCHTHCLMKSFGHLDENGKFDPQSIGDGTDLSDIGMADLEKCYEEYQASDDKCEYAYCVITTMENVE
75 A0A2A4J7D8 Heliothis virescens Odorant binding 115 MTADEQLLTQYSTECISEAGKNLFVDPKQAKENNYPVDADLNAVKDISRCMMVKFGVIDPEGKVNIEGAAKYVSSITGLTKDEATEIVKKCAIVADTDNEESAIKLIECAGKTAV
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