Odorant/Pheromone Binding Proteins

OBPs, members of lipocalin protein family, are highly diverse, small, water-soluble, globular, ligand specific proteins present in the mucus fluid produced by nasal glands in vertebrates and in the sensillar lymph in insects. OBPs act a “carrier” to transport odorants across the hydrophilic mucus layer and release them in vicinity of their respective ORs. OBPs are highly selective, as they have unique ligand binding profile. OBPs functionality and expression are not limited to olfaction mechanism and olfactory organs. They are found to be involved in various other functions like measuring odorant concentration, deactivating odorants, etc. and found in taste organs, venom glands, sex hormone glands, etc of insects. Structurally OBPs are made up of eight antiparallel β-sheets folded into a continuous hydrogen-bonded β-barrel and a α-helical domain at the carboxyl terminal. OlfactionBase comprises of 2418 Odorant binding proteins, 399 Pheromone Binding proteins and 14 receptors from 189 species.

obp
Sr. No UniProt Organism Type Length Sequence
76 Q9TVR8 Agrotis segetum Pheromone binding 115 SQEIMKNLSLQFAKPLEDCKKEMELSETVITDFYNFWKEGYEFTNRQFGCAILCLSSKLELLDQDLKLHHGKAQEFAKKHGADEAMAKQLVDMIHGCSQSTPDVADDPCMKTLNV
77 Q9UA26 Agrotis segetum Pheromone binding 115 SQEIMKNLSLQFAKPLEDCKKEMELSETVITDFYNFWKEGYEFTNRQFGCAILCLSSKLELLDQDLKLHHGRAQEFAKKHGADEAMAKQLVDMIHGCSQSTPDVADDPCMKTLNV
78 Q9UA29 Agrotis segetum Pheromone binding 115 SQEIMKNLSLQFAKPLEDCKKEMELSETVITDFYNFWKEGYEFTNRQFGCAILCLSSKLELPDQDLKLHHGKAQEFAKKHGADEAMAKQLVDMIHGCSQSTLDVADDPCMKTLNV
79 A0A182GED9 Aedes albopictus Odorant binding 116 MARLLLVLVFILHGCLVDTPQHPDDSDLLERIQYHRNVTDDPLTKEFILCGQKLLGWQDSEGNFQNEVIIKFFSDRYDAEQVKEVIEQCTLPSGETLADRAYGFYQCYFKHKKYAI
80 A0A182P8R7 Anopheles epiroticus Odorant binding 116 MMKSGEMIRSVCLGKAKVSEELVNGLRDSKFVDVKELKCYVNCVMEMMQTMKKGKLNYDASVKQIDTIMPDELAGPMRAALDICRTVADGIKNNCDAAYAMLQCLSKNNPKFIFP
81 A0A182UB66 Anopheles melas Odorant binding 116 MMKSGEMIRSVCLGKTKVAEELVNGLRESKFADVKELKCYVNCVMEMMQTMKKGKLNYDASVKQIDTIMPDELAGPMRAALDICRTVADGIKNNCDAAYVLLQCLSKNNPKFIFP
82 A0A182VME1 Anopheles merus Odorant binding 116 MMKSGEMIRSVCLGKTKVAEELVNGLRESKFADVKELKCYVNCVMEMMQTMKKGKLNYDASVKQIDTIMPDELAGPMRAALDICRTVADGIKNNCDAAYVLLQCLSKNNPKFIFP
83 A0A1B0CD47 Lutzomyia longipalpis Odorant binding 116 MQKAGELVRSICQPKFKISDEQANGFGKAQFPDDKNSKCYVNCIFENIQSMKRGKFQFEATKKQAEILLPDDMREASIKAMVACKGATDGIKDPCEAAYSLLKCLHSNHEDFFFP
84 A0A1W4VDC6 Drosophila ficusphila Odorant binding 116 MKRLLVSVFLVGFLVQATSAAGLIPEAAVYAAQCAKEQRVPLKLAMSVVTGPFLIRKTKEIKCFIKCFAEKANIFEKNRNVLEGQQNKCDFFKNADDCDDAFQKFECILKIVKRIL
85 A7VJH7 Anomala schonfeldti Pheromone binding 116 MSEEMEELAKQLHNDCVAQTGVDEAHITTVKDQKGFPDDEKFKCYLKCLMTEMAIVGDDGIVDVEAAVGVLPDEYKAKAEPVMRKCGVKPGANPCDNVYQTHKCYYDTDPQSYMIV
86 B0XK45 Culex quinquefasciatus Odorant binding 116 MPNLPTKTLIKSEENAFQACIEQEGASKVDADVVRKLNVPQTYTQKCLYACMFEQSGTSDGQQFDKDTFLTNAGKMANVDQKAVQRMADRCDGVENDDRCELAADIVACLSGRKRS
87 H9JFQ8 Bombyx mori Odorant binding 116 MYTNFILIFYFGISIYDVRASSLDDLKMVYKNVIKECVGDYPITAADLKLIKARQIPNDDIKCVFACAYKKTGMMTEEGMLSVEGIKDMSQKYLSDNPEQLRKSKEFAEACSSVWL
88 M1T4J0 Brachysternus prasinus Pheromone binding 116 MSEEMEELGKQLHDDCVGQTGVDEAFITTVKDHKGFPDDEKFKCYLKCLMTEMAVVGDDGVIDVEAAVGILPDDIKDKAEPVMRKCGAKVGANPCDHVYLTHKCYYDTDPETYMIV
89 M4W9C1 Dendroctonus ponderosae Odorant binding 116 MKSLVVFCALLVMALAHDPHGLDSVHKECHNEVASQHYLCMAKGLHLVTPEGKVNVNGVKTHAGHVVSESAKIDQIAKECAVDHASTEETVNHLFKCLEEKHVLSLAGHVAPQHHH
90 O77074 Anomala osakana Pheromone binding 116 MSEEMEELAKQLHNDCVAQTGVDEAHITTVKDQKGFPDDEKFKCYLKCLMTEMAIVGDDGVVDIEAAVGVMPDEYKAKAEPVIRKCGVIPGANPCDNVYQTHKCYYDTDPQSYMIV
91 Q8MYB3 Anomala octiescostata Pheromone binding 116 MSEEMEELAKQLHNDCVAQTGVDEAHITTVKDQKGFPDDEKFKCYLKCLMTEMAIVGDDGVVDVEAAVGVLPDEYKAKAEPVMRKCGVKPGANPCDNVYQTHKCYYETDPQSYMIV
92 Q8MYB4 Anomala cuprea Pheromone binding 116 MSEEMEELAKQLHNDCVGQTGVDEAHITTVKDQKGFPDDEKFKCYLKCLMTEMAIVGDDGIVDIEAAVGVLPDELKAKAEPVMRKCGFKPGANPCDNVYQTHKCYFETDPHSYMIV
93 Q95YN2 Exomala orientalis Pheromone binding 116 MSEEMEELAKQLHDDCVGQTGVDEAHITTVKDQKGFPDDEKFKCYLKCLMTEMAIVGDDGIVDVEAAVGVIPDEYKAKAEPIMRKCGFKPGANPCDNVYQTHKCYYDTDPQAYMII
94 T1H963 Rhodinus prolixux Odorant binding 116 MQDMEVCKNDTKMSDEEFSELMAQQMPKSPEGKCFIFCMMRSMTLMSEEGELNSEGCSAMIAEAPIDDDQKEKMKGMPEECAKEGCEKKEDPCETAYRISLCFQKKAEEVNKHIYF
95 A0A034WGW2 Bactrocera dorsalis Odorant binding 117 MKFFIVMLAVVTLAYAEDEWMPKNDAEVSVIRQECIKDFPLSEEQLQKFRIFEYPEEEALRKYLLCVTKAVGIFTEHEGYHADRVAKQFNINLDEAEVTIIAEGCADKNVEGSSADV
96 A0A0M4ELZ9 Drosophila busckii Odorant binding 117 QYPPSNVLKMAKIFHDACVEQTGVSEAAIKEFSDGEIHEDEKLKCYMNCLFHELEVVDDNGDVHLDTLYHSVPHSIRAHLMDMSAKCLHPVGDTLCEKAWWFNQCWKKADPEVSLSA
97 A0A0T6B5K4 Oryctes borbonicus Odorant binding 117 MKQFIVVAVLCVIVYVQALTDEQKAKVKVASEKCVGETGVDPKLVAQGRQGEFVDDPKLKQFILCFLKATEILDDNADVRADKVKEKLSKDVSEAELDGLLTKCKPAGSDPVEKASG
98 A0A182J6A3 Anopheles atroparvus Odorant binding 117 MVTVGEHRKTYKKAGSVAAESRYDYHTYGNIYVPQDAKMSYGRKTVADDVKRGIFAETKEFKCYISCLLDIMQVARKGKVNYEKSLKQIDTVLPDAIKPAFRAGLEACKDVGTYQGR
99 A0A1W4VE93 Drosophila ficusphila Odorant binding 117 MKVLGALLFLLFIDSIFCFEDYLEYDRYFSNCTTRNEALKEITKLQIREVHSEAKCFYHCVFESKGVIVNGKIVRNPFDETPEKAEKTKPCLAIENSNKCELAYKLTECFSKQLGTI
100 B4HRT1 Drosophila sechellia Odorant binding 117 MKVFIGLVLLMAVASLSSALFESEAKECAKKLGITPDYFENFPHSSRVKCFYHCQMEKLEIIANGVVTPFDLKVLNITPESYDKYGVKVKPCLTLSHRDKCELGYLVFQCLKREFNL
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