Odorant/Pheromone Binding Proteins

OBPs, members of lipocalin protein family, are highly diverse, small, water-soluble, globular, ligand specific proteins present in the mucus fluid produced by nasal glands in vertebrates and in the sensillar lymph in insects. OBPs act a “carrier” to transport odorants across the hydrophilic mucus layer and release them in vicinity of their respective ORs. OBPs are highly selective, as they have unique ligand binding profile. OBPs functionality and expression are not limited to olfaction mechanism and olfactory organs. They are found to be involved in various other functions like measuring odorant concentration, deactivating odorants, etc. and found in taste organs, venom glands, sex hormone glands, etc of insects. Structurally OBPs are made up of eight antiparallel β-sheets folded into a continuous hydrogen-bonded β-barrel and a α-helical domain at the carboxyl terminal. OlfactionBase comprises of 2418 Odorant binding proteins, 399 Pheromone Binding proteins and 14 receptors from 189 species.

obp
Sr. No UniProt Organism Type Length Sequence
101 E9JC82 Solenopsis invicta Odorant binding 117 FIKLVSFCVYVGARADIKRECRQQTNVSWASLKQLKAGNIEQNDMKLKCYLKCFMVKIGILNEDSNVDVEKALRHLPRSMQESSKRILNQCKLIQAENACDRAFQIAICYVKAQPEV
102 Q8MVX6 Drosophila melanogaster Odorant binding 117 MRVLLAFVLLLGLSVLATKEPEEVKIVSECAKENNVHRKKALDLLMSYRLKKKTHNVMCFINCIFERTNILQKVKEKVVKENHNCDSIKDADKCAESFQKFQCLVKIEMKVRGIDRG
103 U4UNM4 Dendroctonus ponderosae Odorant binding 117 MGPTILLLVGLVMMTNAYVPNVNNKIRDFCIDDSGVSIEMVENLLANPEKQLIDVESCYVHCIFTEMGLLSENGNVEVEKFKSLKASEAPYIDLTCLEEIKSIDHCNEMMILRACHV
104 A0A0Q9X9F8 Drosophila mojavensis Odorant binding 118 MKLKTYIFITIILTLLCFSYSNEICLKLNNVTIADLNNIPINVPIEDLPDKFKCYCRCLLKDILDENGKMDVELALNSYPVAYVEKVKTCKKRYDHMESESCNYAAFAFSCLHFEQIT
105 A0A182Q284 Anopheles farauti Odorant binding 118 MDQMAKTSAMMRSICMAKHKASVEQIDGLGRGEFVDTKELRCYANCVLEMMQAMKKGKIIADSAIKQVDLLIPTEIAEPTMKAFDRCRDAANGIKSPCDAAFALVKCLHANNPKYFFA
106 A0A194PWY8 Papilio xuthus Odorant binding 118 MVVKTTTLLFLCTVLVGITTARKATIGVPSDIVGLWNVSPKPELMLTSYSKAGFSDDTGHFHKDKILALYEKSDKKEEIKAAVDACDKIAEKNPLETMYKVILCFFDKTPVLLEVKLD
107 A0A195EYF4 Trachymyrmex septentrionalis Pheromone binding 118 DVMLTVHDITHDRYKSESEEKLNKNGCVMQCLLQKAGLASNAEYKVEKMHSEFIKKTGVQPGDQRLECLDTCINESKDLTEKCVKAFNLSACVIKFEHRHKHENDHEHDHEHENESAK
108 A0A1I8Q246 Stomoxys calcitrans Odorant binding 118 MTQDEAERLAADIIIKCGHEVDISKQETLNLFPETSSAIGNMTDKMKQFMLCFYKKLELIDATGKPDVEGFTLYLENRFPAKKHKVKPTLAKCLEGQTADTFEAMGKIDICLIKNILE
109 A0A1W4VCX2 Drosophila ficusphila Odorant binding 118 MKVLGALLFLLSIDSIFCFEDYTDRYLLNCTTRNEALKEITKQRQTSSDLKCYYHCYFESKGVMVNGKIVRNPFKKTLEDAKKVEPCLAIENPNKCELAYNLIQCFTKQLGIFVLLKQ
110 A0A1W4WCX2 Drosophila ficusphila Odorant binding 118 MKVLGALLVLLFIDSIICDPDRFETVLHNCTTSTEARKELTKIRTQEVQFEPKCLYHCFFEASEIITNGKINQSGFNTAAEDAEKAKPCKAIEDPDRCELAYKFEECVKEQLNFSFFS
111 A0A232F462 Trichomalopsis sacrophage Odorant binding 118 MKSVLVVFAAICIAGVLSDTKGDIDACVAESKVDTKLFEHMMHTPNFKATREMDCFAACMFKKDGVLDADGNVDASKLPNVDVSKVCGALRGKDACETAGKIMGCFAEKGVMDVFHIE
112 A0A2K8GKR6 Dendrolimus punctatus Odorant binding 118 MEEFFHFWHEDFKFVHRELGCAILCMSRHFNLLTETSRMHHENTDNFIKSFPNGEILAAKMVEIIHTCELRFENEADHCARILRIAECFRDTCKSVDLAPTMEILMAEFILQAESGKR
113 A0A482VSY0 Asbolus verrucosus Odorant binding 118 MKFLLILSSLILGTIAIDQSFLEAARSKIKKKLVECIDEEHSSQSDLDEILALHVPASHEGKCAIFCTHKKFDLQHEDGSINQEGALETFEIIKEVDEEFYQKWVNVFNSCSSSKVLT
114 B4MTE6 Drosophila willistoni Odorant binding 118 MQAAGKLMRDVCLPKYPKVTEDIANDIKNGQLPNNKDANCYVNCILEMMQAIKKGKYQLESTLKQVEILMPESYKAEYRAGAQACKDATNGIKNSGNCDAAHALLTCFKNNIKIFVFP
115 B4QGD1 Drosophila simulans Odorant binding 118 MKVFIGLVLLMAVASLSSALFESEARECAKKLGITPDYFENFPHSSRVKCFYHCQMEKLEIIANGVVTPFDLKVLNISPESYDKYGVKVKPCLRLSHRDKCELGYLVFQCLKREFNL
116 Q7KE33 Drosophila melanogaster Odorant binding 118 MKVFIGLVLLLAVTTLSSALFESEANECAKKLGITPDYFENFPHSSRVKCFYHCQMEKLEIIANGVVTPFDLKVLNISPESYDKYGVKVKPCLKLSHRDKCELGYLVFQCLKREFNL
117 A0A026X3I9 Ooceraea biroi Odorant binding 119 LILYVRTRADIKRVCRRQTSVSWASLKQFVKAGNIEQNDMKLKCYLRCFMVKSGILNEDNNVDLEKALRHLPRSMQETSKNILNQCKSIPAENACDKAYQIAVCYVKEQPEILKNPAFI
118 A0A0A9Y9A5 Lygus hesperus Pheromone binding 119 MKSFVGLIFAVALVEFASAVTKEYHDRAVAAKDKCAKEHNIKESEIQEFLKKHKLPETEDGKCMIACYLEEMKLITDGKVNVEEWKKSNKEKWDEEAHVAMADEIVDKCNEQGQFYITR
119 A0A0T6BBU7 Oryctes borbonicus Odorant binding 119 TVAEIMWKYITAVLFLSTSVISLDGILMRLIEQKDICIKELNLNETEINTLKIKSLQGMELSHREQCVVACMLQRAGFVENGKLNSDVLKKSIPDDISLDLGKCEELTGSDDCETSLKI
120 A0A182FQ67 Anopheles albimanus Odorant binding 119 MMQLQNTAITFRQVCQSKHPGVTDVDASTVSKGIFAETREFKCYLSCLLDIMQLARKGKINYEKASNQLQTMLPDDLKQDALLALAACKDVAREIRDHCEASLMLVRCFYENNPHFVFP
121 A0A182SD77 Anopheles maculatus Odorant binding 119 MKQMSLLWPALLVIGAVLIGCCSSKSTLDQMAKTSAMMRTVCMGKHKANEDLIDGLGRGDFVDMKELKCYANCVLEMMQAMKKGKIAADSAIKQIDLLIPAEIAGPTMKAFDGCRDSGK
122 A0A1B0C832 Lutzomyia longipalpis Odorant binding 119 MFAHGIEIPSSMMSNLLSCGKDSGITAEDLLNVYKGNFSVLTKFNGCIIDCFTKKIGLLSEDNKLNNEDFKKRVSGLFNAEHSEKLFDECSAKATTTECEASAPSVICSVIYALVTAFS
123 A0A1B0GFV6 Glossina morsitans morsitans Odorant binding 119 MQVLQNNYICKTLQNYVKTCVIEENISTKDLKLFMAWNFSNISNEGKCFFSCFHEKIGLTINGVLQKKIAFGHLKRIFDRETAEFVLGECVNLVGKDKCETAYQFEKCLFNIEYNRLAK
124 A0A1I8MFV2 Musca domestica Odorant binding 119 MNFFNIALCVALAVVFVVGKTSADHAACLDKNGLSQDEFDSIVKKLEDGAEDADTKFKCYTHCMMESDGLIDGSGKFDVSSLDDGEDKDEAEKCKKEYDGVSDKCEYAFKLSNCYFKHE
125 B0WU11 Culex quinquefasciatus Odorant binding 119 MKIILAFCLFTAVAALELSPEEKKCQEQVDASEEDVEMFRSLQQPEERTTKCYYDCMLQKINYSDGKRFNREGFLHTMTQVAKNEQQRKAIQHLGDQCNGTENDDPCELAADIVACLFR
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