Odorant/Pheromone Binding Proteins

OBPs, members of lipocalin protein family, are highly diverse, small, water-soluble, globular, ligand specific proteins present in the mucus fluid produced by nasal glands in vertebrates and in the sensillar lymph in insects. OBPs act a “carrier” to transport odorants across the hydrophilic mucus layer and release them in vicinity of their respective ORs. OBPs are highly selective, as they have unique ligand binding profile. OBPs functionality and expression are not limited to olfaction mechanism and olfactory organs. They are found to be involved in various other functions like measuring odorant concentration, deactivating odorants, etc. and found in taste organs, venom glands, sex hormone glands, etc of insects. Structurally OBPs are made up of eight antiparallel β-sheets folded into a continuous hydrogen-bonded β-barrel and a α-helical domain at the carboxyl terminal. OlfactionBase comprises of 2418 Odorant binding proteins, 399 Pheromone Binding proteins and 14 receptors from 189 species.

obp
Sr. No UniProt Organism Type Length Sequence
201 G8B1L4 Nasonia vitripennis Odorant binding 124 MKAVVIVLAVCLAGVFAEDPIKDINKEYIKGCLIENGFDPQQYPTGLRNAKVPEKQEQNRNCYYSCMMKKMNLMKADGSLNEDALRQKFNMNLDTLGKALSTCKDQVKDDKCKLAACLMANRGA
202 G8B1N3 Nasonia vitripennis Odorant binding 124 MKIFVIVALCAVAVYAEENEVLKQYERDCMTENGIDPTVQDPKNLTLEDGNCYYACYFKKFGIIKEDGSYDVAAIKEKYSKPNSVEAVQKKLDEITQTYCQDKVGNHCNLAACLSKISKEQWKI
203 H9JSV4 Bombyx mori Odorant binding 124 MGLTETVLKDFYNFWIEDYEFTDRNTGCAILCMSKKLELMDGDYNLHHGKAHEFARKHGADETMAKQLVDLIHGCSQSVATMPDECERTLKVAKCFIAEIHKLKWAPDVELLMAEVLNEVSWKS
204 A0A0K8U8Z7 Bactrocera latifrons Pheromone binding 125 DEFGEKVKKMAGECKEQVGASDDDVARLFKYEPAANDKAKCLNACLMKKKIGILDENNKVIEAAAIAYVKQVSGGDAEFEKLSMETYNECKSTPESSDECEYAEAFRQCVIESAKSKDIKILPQI
205 A0A182PLJ0 Anopheles epiroticus Odorant binding 125 SITQEQLEKTAKTFRQVCQPKHKISDDVADGVNRGVFAETKEFKCYVSCLLDIMQVARKGKVNYEKSLKQIDTMLPDNMKPAFRTGLEACKTAGKANGLGIKDHCEAAAVLLQCFYKNNPKFVFP
206 A0A1A9ZKM4 Glossina pallidipes Odorant binding 125 MMDKNGDWDVTRQQFEQSLAMMRNGCAPKFKLTTEQIDGLRLGNFDENNKDLKACFIILTKKGELSAQKALAQIPMILPVEMQEIALASLEHCKDIQKNYKDSCDRLFFTTKCVYEYAPDDFTFP
207 A0A1B0FAV8 Glossina morsitans morsitans Odorant binding 125 MAIFIFVTMKAADTVDFDDVIEECNSSFSIPTDYLTSFNSTGSLPDVTDKTGMCFLRCFYEKSGFIKNWKLIDAKIRKYMWPATGDSIEICEQEKSKEPNSCVRLYAIIKCLMLRAIVDARNKPV
208 A0A1I8NER2 Musca domestica Odorant binding 125 MKVFWILIFLAAADCDEIVKPNTRCSGEFLQNAIKRCAQAYGATEDDLKDVIYFKPAANHKMKCFRACVFTECKAFTNDGSLVANIPQTTAFLTSRRNASHYQIVEEIGEDCLNKLSSYDDTYVK
209 A0A1I8NL52 Musca domestica Odorant binding 125 MNLKYILIFSLFCGAAYIKADLDSLSLAMKDCLLKHSITQKEMDMFLENMYANVTENFKCSMKCVLEKEGIMKNGTFDDKTFEKKALSVSLLKGQEKQVIQAAEKCKNIKGSNDCDTAYKIVLCL
210 A0A2A4IV42 Heliothis virescens Odorant binding 125 MVSSFAYGRISVMYAHDKLSDMVAQQCLSEMYPKNKRIEIQESDEPCIIFCVLKKFGIMSATGVIDLENYRKRVKIAHQLDQRNGISDYGGTCIENAEATQHKQDVCKKAKVFNDCTHLYRILLK
211 A0A2A4K7S5 Heliothis virescens Odorant binding 125 MSEEEKAAIITAITPLAQNCGSECGLDNDDFEKYKEDGSNMDPCFKACLMTQMGVLDKDGKYDGKGLHKAMEEADYPGDKEDAQKFLDELDRCFDAKGDNDGDDEEAKMKRADVLFQCMQDMKEK
212 A0A2K8GKQ2 Dendrolimus punctatus Pheromone binding 125 MNQCIKEMDLPDVSADFYNYWKEDFVITRRETGCLFSCLAKKVSMQHSDGLLHKDNTHNFATKHGADDEMAAKLVETIHACENSISESDDCVRVLSIANCFKKEMHKLNWAPSAELVTQELMAIL
213 A0A2S0M1E7 Corythucha ciliata Chemosensory 125 MMGQASFFVLVLLFLGITGQTPSLDEVFDESIDVDDILDNDRILDTYLKCFYGTAKCNTLASAIKERIPDIFSTVCGECTEKQKGIFKHVLVKFIPKRPDDWELILKIYDPKGEYRPKLEEFIKS
214 A0A3Q0ITI2 Diaphorina citri Odorant binding 125 MQQWIYFRLFIFNHNSCSQSLFLYFLFSLFLYLFQCLLQCVYRKVKAVDSNNFPSAEGLVRLYSEGVQDRNYFTATYQAVQFCMKLAEQVRQSKPNGVLDGGQTCDLAYDMFNCVSDQIEKVSQI
215 B4JYH4 Drosophila grimshawi Odorant binding 125 MSGLSQAKVYPPPELLKALAPVHDTCVAKTGVTEAAIKEFSDGEVHEDEKLKCYMYCVFDETDVLHEDGEVHLEKLLDRLDSMHDIAINMGKRCLYPKGDTKCERAFWLHRCWKQADPKASIPAS
216 B4MRT7 Drosophila willistoni Odorant binding 125 MGLNEQVMSQSAADMAAFKQMQDGCIKELNIGTAEAALIATDKPVANPTESYKCYHNCLYKKMGMINADGKANNDAILKIITTRYAKAPVDKVKALLTSCGAAPSTNACDYAYKFEMCMINGLKA
217 Q7KE32 Drosophila melanogaster Odorant binding 125 MKVFLLFIFISAIWLQAFCMKSSEKIKACLKRQLGYTITENTKFDAKEDSLQSKCFYHCLLEVKGVIANDAISSEQPRKVLEKKYGITDTDELEKAEEKCHSIKASGKCELGYEILKCYQSITKH
218 T1GMW4 Megaselia scalaris Odorant binding 125 MKAFLVFAVILAVAVAEMHEMMGEQFKKECMDQEKVDASELEKVRSGQLDNPSEKLKCFNRCMFEKGGFFKDGMFVDEKVKEFLNKHTQKEHMLTAYEDCKKIKGTNDCDTTFKVFECMHKAHMP
219 A0A034WH85 Bactrocera dorsalis Odorant binding 126 VAVAAAQEGVNKLTEEQKQKARALGTECLKETGASEEAIRALIKGDDSQVDGKVKCFSKCMQEKLGFVENGKVNEEKVQNILGKLIGEEKAKATQAKCNGLKGTDECDTAYQIRQCYSAGYNGFAF
220 A0A182GHF0 Aedes albopictus Odorant binding 126 MNAHQKSTMEQMAKASEMMRGVCIGKTIAPMDLVDGLGRGEFAENKDLKCYANCVLEMMQAMRKGKVNADGAIKQVDLLIPVEIGEPTKKAFDICRNSADGIKNNCEAAWALVKCLHQNNPKYFFA
221 A0A1B0GG08 Glossina morsitans morsitans Odorant binding 126 MLERYNAEIDEETQALERECLKEENIPGRFNLPNYSLTDHFLGQIEYAEIAPKNAKCFLRCWYKKMGILKENLVTSAGPIPELRQHMRECNEVATEWAQNQSNGDECEFAWSFYTCMHESLVKCLT
222 A0A1I8M486 Musca domestica Odorant binding 126 MYRQCTVLVLALLIFVGKISTEDTSKHTACLEENQMSEDELYNILDEIKAGATEIDRRFKCYTFCMMQSWEHLDENGILDMSTLKHHSNMTESEVEPLEKCTEEYRGSDDKCEYGYCVIAALGNMD
223 A0A1J1IC31 Clunio marinus Odorant binding 126 MNLKLLQTLLRKAFTTMKKCGNAINHSISTLELNDTGSFPDEVEMTPMCFLKCYLESIGVLDKELQINRVKAVELYNLNDDSETYDDCADDMSSENVTDECEKAYFFVRCVMSRKLFDNLEEDEMV
224 A0A1W4VE88 Drosophila ficusphila Odorant binding 126 MKVLGALLFLLSIDSIFCFEALETPDNCTTLEKAQKEIKKQSFYSVTNDFKCFHHCVFEYNKFIVDGKIVKDAASRIASTPEEVKQVKECHDVTDPDRCELASKWFNCVRERLGGVRFEKALSYYQ
225 A0A232EK66 Trichomalopsis sacrophage Odorant binding 126 MGGFVTVLYFLSIIICVYSLNWSEAKKHVQECLDEYQITREDVAKLKKEESLDYNCYIACIMKKRGSLVDGKIDEEKMLEILKQLHVLNSERTEDKFRICATEANKQSNECMVAGDMIGCLYFKSN
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