Odorant/Pheromone Binding Proteins

OBPs, members of lipocalin protein family, are highly diverse, small, water-soluble, globular, ligand specific proteins present in the mucus fluid produced by nasal glands in vertebrates and in the sensillar lymph in insects. OBPs act a “carrier” to transport odorants across the hydrophilic mucus layer and release them in vicinity of their respective ORs. OBPs are highly selective, as they have unique ligand binding profile. OBPs functionality and expression are not limited to olfaction mechanism and olfactory organs. They are found to be involved in various other functions like measuring odorant concentration, deactivating odorants, etc. and found in taste organs, venom glands, sex hormone glands, etc of insects. Structurally OBPs are made up of eight antiparallel β-sheets folded into a continuous hydrogen-bonded β-barrel and a α-helical domain at the carboxyl terminal. OlfactionBase comprises of 2418 Odorant binding proteins, 399 Pheromone Binding proteins and 14 receptors from 189 species.

obp
Sr. No UniProt Organism Type Length Sequence
251 A0A1A9XZG5 Glossina fuscipes Odorant binding 128 MEKYNIFLFILFQMPLFDLQGTESFRELCQQIHNITDEEFESFNAFEAIDVEPDRKFKCYAHCLLSHLKYLNLFSGKFDIDDFKQQDGIEDEDVAVIAKCKKLYDNISDPCEYGFKIMQCILMFEPTK
252 A0A1B0DGX3 Phlebotomus papatasi Odorant binding 128 MSKAVEKGVTYEQFLQNAKSLRKTCQPKHKVSDELADQLGKKNFPEDKNLKCYVKCFLEMAQTMKRGKINVEAAIRQIDILVPEHLRNDYKATVQACKDSFKGIKDNCEASYIFLKCSAEQNPSYEFP
253 A0A1W4VEJ3 Drosophila ficusphila Odorant binding 128 MKVGQRTLFLWIFLIAMWEFPGSFGDEDCLKNHNLTSADLEEVNPSTPVSAVPINIKCYSRCVIDEYFGEDGKIDLERVGNRGTEQEKIVLAQCKQQFDDVTDLGRCDYPYLMLQCFYLGKRSGTIAQ
254 A0A2S0M1E0 Corythucha ciliata Chemosensory 128 MKAAPGVIVVLLVAVCSVTQAGESKYTTKYDNVDLDEILRNTRLYDRYIKCLTNKDDCSPDGKELRDILPDALKTKCAKCSEKQKSGAEKVLKFIYEKKRTDFDELEKIYDPKGTYRKEYEVILKKAH
255 A0A2S0M1E5 Corythucha ciliata Chemosensory 128 MLDTRLIILAIALLATGVWSYTSRYDNVDVEEILKNQRLYSKYFTCLTHTDASKCTTDGRELRRIVPDALATGCSKCTAQQLDSATKVIKYISEHKPEDFKKLLALYDPTGEYKRTFATKAAERGIKL
256 B0W4L1 Culex quinquefasciatus Odorant binding 128 MKLVVTLLISLAAGAFSVKAEYSKKRVEEVLKVGNQCKQELSIPEEDNVIERALTRNDMRYMLCFYSKFNMLDANDNIVVDKVVNFMVEQYAEQVIRPVVTRCAKQGDPSVYDRLWKFYQCISTDKSW
257 B4JYL4 Drosophila grimshawi Odorant binding 128 MTSRADAWQLPRAKDVQHSLESCHAEQAGEDAATLRCLVDQLGLWTDELGYNARRITKIFAAYNQMEELILVIDYCNSKERREKEPAQWAYNAYKCATSGRFGEWVNDYYVKQLQAVKSKPESRFDED
258 B4R7A8 Drosophila simulans Odorant binding 128 MKVVCSIVVLWTCLITMWQSAGHVSAEGCLKHHNLTSAQVEAVAPSTPVAEVPVAVKCYSRCLIQDYFGDDGKIDLQKVGKRGSEEDLVILSQCKQQFDGVTNLDTCDYPYLILQCYFKGKQSGTIAS
259 D6X0T3 Tribolium castaneum Odorant binding 128 MSKTVFIFVIFFYLDFYATGDESVYLSNHEACVKLSGVDETLLETIYEGDVFEDMKFKTYIHCFFKKSGFQDENGVMHFDAIKSSFHKDFSQTENIDKTITECEEKKLNGESALETAFLHFKCFMGEL
260 Q8T5U0 Rhodinus prolixux Odorant binding 128 MKTIAVIAIVCYLFVATESFPSHSPELDTCSTKHHLSKDRARQLAIHSVQATDDNEKCFLSCYLKERGYLVDGRVDFDKLLENHKKFQPTLFEELKKTFDECKKNLDYNGKNECEVAYQAYSCAFTRP
261 T1H857 Rhodinus prolixux Odorant binding 128 MNMLTILATFCFLIAAVNCRVLKQEDALEKCSKENSIDRELAQKIISHQAHATTPNEKCLIACYLKVKRYLLNHQIDWVAIYKSHAARITDETEKEKVKAIFEECEANSYENKDDCQIAYDAYECKKL
262 A0A067QNG6 Zootermopsis nevadensis Odorant binding 129 MLLVSTAIVIVLVGTAIGESRFDSLDDDQKAMLKMLHDTCIDESGADEALIQKAMKGDFAEDDKLKGAMDESGVPDMDTMVSMLPESMQERGGKMIGVCKSITGSSAPDTAMKLNQCFYKADPEYFFII
263 A0A0A1XJG7 Zeugodacus cucurbitae Odorant binding 129 MVAGKFQIRTAQDALAAHEACHDEFRIPEDIYEKYLNYEFPPHKRTNCYVKCFVERMGLFTEEKGFDEKAIIAQFTAKSSKNLAKVSHGLEKCIDHNEHDSDTCTWANRVFSCWISVNRPIVRKTYIEN
264 A0A0B4JD42 Drosophila melanogaster Odorant binding 129 MVVCVQRTQVQAGPIKDQCMAAAGITAQDVANRHETDDPGHSVKCFFRCFLENIGIIADNQIIPGAFDRVLGHIVTAEAVERMEATCNMIKSETSHDESCEFAWQISECYEGVRLSDVKKGQRTRNHRG
265 A0A0N0PE48 Papilio machaon Odorant binding 129 MDTEPSLSILYAQDKRSDLVTNDCLLEMYPRNLYKYPLRIDRNDIPCVIHCVLKKFGIMSNDGVINIQNYYKRVRAFHRNDPRVLISDVGETCAQNINGMNLDHDVCKKAKVFNDCTQLYVISYKDADD
266 A0A0T6BA51 Oryctes borbonicus Odorant binding 129 MKRFIVSILLIGIIAMVHAKPSMEKLDQYREACAQEVGISLESVTHPPLSSGPPPEPSKDMKCFMRCVLTKAGIFDSNGALQTSKLHLPEDATNVDLSKCTSITDSDPCQQTYLIEVCIRQQLPKPPSK
267 A0A182GPP3 Aedes albopictus Odorant binding 129 MIIVTASSRCTIACDEDDDDVPDSRSSEESTTPGYSIESIYAECNDSFVTTMEYLETLNKTGRFPEESDLTPLCFLRCFLHKSGVYDELENVKGEMAVEIGWVESVQTIDECVEEMGKFEYDILESIYK
268 A0A195B1V6 Atta colombica Odorant binding 129 MKTIVILLAVSFVTVLGKVTEEDQAKWVKNEKDCIDESGVDPAVLHKGKEEESDENDEKLACYKSCLLKKFGILKEEKIDWDKFRVEMSKYDTSQEKIDEMYNKCKDIDGEGCQKGKNLMKCLQDVKDD
269 A0A1A9WX28 Glossina brevipalpis Odorant binding 129 MSNNEIPKNMQQFQDMLNETKFKCAATMRLNPNKLLMNEDQPTMKEKCLMACILKRMKLMDPDYKLSVPTISQIAGMISNENPLLISIAAATASKCNTAINAKEPCEAANLINKCIAGELKAHKLNLIY
270 A0A1B0C1L4 Glossina palpalis gambiensis Odorant binding 129 MSSKSPRKRQLYPPPDFLKFFKIIHEVCVEKTGATEEAIKEFSDGEIHEDPALKCYMNCLFHEVDVVDDAGELHFEKLVRMIPEPYLKMFQHILDACVSHIPKGETQCDRAWSWHVCFKQTDPVLYFLP
271 A0A1I8N0P6 Musca domestica Odorant binding 129 MKFYLCLSICAVVLMGGALAEYEEYKEMATKCMEQNNITEDEFEAIPKGEDFDPETLDERFKCFTHCMVEDMGYLDETGKLDLSKLEQDERVTQEHMDAAIKCKAENEFIDEPCEYSFKMMTCALDAMM
272 A0A1J1IB01 Clunio marinus Odorant binding 129 MKLFIVAALLIVAVQGDYVLKTLDDLQTARKECILENKVPQELVAEYQKRIFKEEGVTPCYIRCIFTRLGLFDEKTGFITENYLKQLGRGDTVKDGVVGCYDNTGTDTCLWAYRAFTCFTKQGFLPEGY
273 A0A2S0M1D4 Corythucha ciliata Chemosensory 129 MFTVRLSVALVLAMCVVSAWSYTTKYDNIDIDEILKNQRLYSKYLTCLLHTDATKCTPDGKELRAALPDALSTNCKTCSPKQKAGTEKVIRYMIQHKASDFDKLEKIYDPAGVYRKRYQAEAAKKGIKL
274 D2A056 Tribolium castaneum Odorant binding 129 MKSFVIFVLIIVITGQINATPSLDDFKKVQKDCQKKTGVSDESINKVNNLEPVCDDLLLQENALCILKTYEVMDEEGKICPDKLMEVLEPKFGKEKAEKLIEKCTLEKDTPQLLAHATLFCLSVQKYVV
275 D6X4H5 Tribolium castaneum Odorant binding 129 MKVFVCLAVFALVAAAQAETAKEKLRKYSDECKSVSGVSEELLNKVRNHEDVHDPKLDEHGFCILKKAGFMNEAGDILADTIKTKLKENSEHPDTVDALVEKCNEKKDTPQHTASHLFTCLVDKKVHSH
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